Human Microbiome Studies

Human Microbiome Studies

Microbiome studies using clinical samples (stool, bronchoalveolar lavage (BAL), swabs, biopsies, etc.) to determine the microbial populations present in these samples (bacteria, fungi and archaea) through next-generation sequencing (NGS).

TECHNOLOGY DESCRIPTION

Extraction of genetic material and amplification of bacterial and archaeal 16S ribosomal gene sequences and/or fungal ITS2 sequences. The resulting amplicons are analysed to identify bacterial, fungal and archaeal populations.

TECHNOLOGY APPLICATIONS

Recent research has revealed a relationship between the human microbiome and various physiological and pathological states in the human body. We offer microbiome studies using clinical samples (stool, bronchoalveolar lavage (BAL), swabs, biopsies, etc.) to determine the microbial populations present in these samples through next-generation sequencing (NGS). Bacterial populations can be analysed by targeting the 16S ribosomal gene, while archaeal and/or fungal populations can also be studied by analysing ITS2 sequences.

This type of analysis is intended for clinical testing laboratories that lack the technological resources or personnel required to carry it out but would like to offer this service to their clients.

ADVANTAGES AND INNOVATIVE ASPECTS

Few companies currently have the capacity to offer this service because analysing microbial populations is a complex process. At the university, we carry out research projects using this technology to study microbial populations in both environmental and clinical samples, and we offer our expertise to companies that request it.

DEVELOPMENT STAGE

Our team has extensive experience in characterising both fungal and bacterial microbiomes in clinical samples and participates in research projects in which this technology is applied.

APPLICATION SECTORS

  • Molecular Biology of Microorganisms
  • Clinical Microbiology

PRINCIPAL RESEARCHER

Consuelo Ferrer Rodriguez – Plant Production and Microbiology